In The Witcher 3: Wild Hunt's Blood and Wine expansion, the quest Turn and Face the Strange serves as the gateway to powerful character mutations. Players receive a letter that directs Geralt toward uncovering the hidden research of Professor Moreau. Navigating this quest requires solving ancient puzzles, defeating subterranean threats, and uncovering secret laboratories.

Starting the Quest and Finding Moreau's Grave

The journey begins when a messenger delivers a letter from Yennefer or Triss while Geralt explores Toussaint. Reading the attached map directs players to the Orlemurs Cemetery located near Beauclair. Using Witcher Senses at the cemetery reveals a plundered grave and tracks left by a recent grave robber.

Following these clues leads Geralt toward the flooded ruins in the Valley of the Nine. Approaching the submerged entry point allows players to access the ancient underground facility where Professor Moreau conducted his research.

Navigating the Ruined Temple and Portal Maze

Inside the ruins, players face environmental obstacles and hostile guardians guarding the corridors. Opening the main stone doors requires targeting four hidden wall switches using Geralt's crossbow. After defeating a gargoyle, players must place its dropped paw on a central pedestal to open the next path.

The subsequent portal maze puzzle relies on paying close attention to the orientation of the central statue. Entering the specific portal the statue is facing leads Geralt safely through the labyrinth into the true laboratory.

Unlocking Advanced Mutations in the Laboratory

Upon reaching Professor Moreau's laboratory, Geralt must collect missing megascope crystals scattered around the room to view historical research logs. To activate the mutation machine, players need to acquire mutated giant centipede albumen from the nearby nest.

Placing the albumen inside the contraption and stepping inside unlocks the advanced mutation system. These new abilities offer substantial combat enhancements and grant additional skill slots for late-game builds.